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Congress report: 6th VMAC 2024
At the 6th Vascular Medicine and Atherosclerosis Congress (VMAC) in Augsburg in May this year, hypertriglyceridemia was not to be missed. Experts discussed the latest findings in the diagnosis and clinical relevance of severe hypertriglyceridemia (sHTG). Particular emphasis was placed on developments in the classification and genetic diagnosis of sHTG. A further focus was placed on the prevention of HTG-related pancreatitis.
Find out more about the latest findings and practical recommendations from the Sobi symposium "ThinkTank: Severe Hypertriglyceridemia (sHTG)":
Link congress reportVideos
Video
Acute pancreatitis: have you thought about triglycerides?
Hypertriglyceridemia is not only the third most common cause of acute pancreatitis, but also a prognostic factor for its course. Early measurement and monitoring of triglyceride levels are therefore crucial to initiate adequate treatment. In the case of severe hypertriglyceridemia, a lipidologist should be consulted for further diagnostic clarification and treatment to reduce the risk of further pancreatitis attacks.
Prof. Dr. med. Jonas Rosendahl is a specialist in internal medicine and gastroenterology. As the director, he heads the Department of Internal Medicine I (Gastroenterology, Pneumology) at University Hospital in Halle.
Video
Common but often underestimated: hypertriglyceridaemia
Hypertriglyceridaemia is a common but often underestimated finding. Early diagnosis and differentiated treatment are crucial to ensure targeted treatment. This can reduce the risk of serious complications and improve the patient's quality of life.
Prof. Oliver Weingärtner is a specialist in internal medicine, cardiology, angiology and lipidology (DGFF). He works as a senior physician and head of the lipid outpatient clinic at the University Hospital Jena.
Publication summary
Publication insight
Elevated serum triglycerides are independently associated with persistent organ failure in acute pancreatitis
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FCS diagnostic score
If you suspect FCS in your patient, use the FCS score to inform your clinical assessment.1
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Genetic brochure
Explore the genetic landscape of severe hypertriglyceridemia. In this brochure you find essential insights about the genetics and diagnostic steps for managing severe hypertriglyceridemia.
Download as PDFExternal resources
Further information on FCS - Orphanet
Orphanet is a resource supported by grants from the European Commission, gathering and improving knowledge on rare diseases so as to improve the diagnosis, care and treatment of patients with rare diseases.
Visit OrphanetFor patients
FCS cookbook
The FCS cookbook provides recipes suitable for those following the FCS diet, helping patients to make the dietary changes necessary to maintain optimal health.
Download as PDFNutritional brochure
The FCS cookbook contains recipes suitable for those following the FCS diet and aims to support patients in making the changes necessary to maintain good health.
Download as PDFFCS patient brochure
This brochure provides your patient with important information around his/her disease and management his condition.
Download as PDFReferences
- Moulin P, et al. Identification and diagnosis of patients with familial chylomicronaemia syndrome (FCS): Expert panel recommendations and proposal of an ”FCS score”. Atherosclerosis. 2018;275:265–272.
Causes and Pathophysiology
FCS is a monogenic disease with different pattern of inheritance. In 80-90% of patients with FCS, low activity of lipoprotein lipase (LPL) is caused by mutations in the gene that encodes this enzyme.
Symptoms and complications
Learn more about the broad spectrum of signs and symptoms that are associated with FCS.
Diagnosis
FCS diagnosis is based on a three-step approach:
- High triglyceride evaluation
- Identification of candidates for FCS genetic testing
- Genetic test of possible affected genes