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Congress report: 6th VMAC 2024
At the 6th Vascular Medicine and Atherosclerosis Congress (VMAC) in Augsburg in May this year, hypertriglyceridemia was not to be missed. Experts discussed the latest findings in the diagnosis and clinical relevance of severe hypertriglyceridemia (sHTG). Particular emphasis was placed on developments in the classification and genetic diagnosis of sHTG. A further focus was placed on the prevention of HTG-related pancreatitis.
Find out more about the latest findings and practical recommendations from the Sobi symposium "ThinkTank: Severe Hypertriglyceridemia (sHTG)":
Link congress reportPublication summary
Publication insight
Elevated serum triglycerides are independently associated with persistent organ failure in acute pancreatitis
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FCS diagnostic score
If you suspect FCS in your patient, use the FCS score to inform your clinical assessment.1
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Brochure
Genetic brochure
Explore the genetic landscape of severe hypertriglyceridemia. In this brochure you find essential insights about the genetics and diagnostic steps for managing severe hypertriglyceridemia.
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Further information on FCS - Orphanet
Orphanet is a resource supported by grants from the European Commission, gathering and improving knowledge on rare diseases so as to improve the diagnosis, care and treatment of patients with rare diseases.
Visit OrphanetFor patients
FCS cookbook
The FCS cookbook provides recipes suitable for those following the FCS diet, helping patients to make the dietary changes necessary to maintain optimal health.
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Nutritional brochure
The FCS cookbook contains recipes suitable for those following the FCS diet and aims to support patients in making the changes necessary to maintain good health.
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FCS patient brochure
This brochure provides your patient with important information around his/her disease and management his condition.
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- Moulin P, et al. Identification and diagnosis of patients with familial chylomicronaemia syndrome (FCS): Expert panel recommendations and proposal of an ”FCS score”. Atherosclerosis. 2018;275:265–272.
Causes and Pathophysiology
FCS is a monogenic disease with different pattern of inheritance. In 80-90% of patients with FCS, low activity of lipoprotein lipase (LPL) is caused by mutations in the gene that encodes this enzyme.
Symptoms and complications
Learn more about the broad spectrum of signs and symptoms that are associated with FCS.
Diagnosis
FCS diagnosis is based on a three-step approach:
- High triglyceride evaluation
- Identification of candidates for FCS genetic testing
- Genetic test of possible affected genes