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Our details
This website is owned and operated by Swedish Orphan Biovitrum AB (publ).
We are registered in Sweden under registration number 556038-9321, and our registered office is in Stockholm.
Our principal place of business is at SE-112 76 Stockholm, Sweden.
You can contact us:
- by post, to Swedish Orphan Biovitrum AB (publ), SE-112 76 Stockholm, Sweden;
- by telephone, +46 8 697 20 00;
- by email, info@sobi.com
Last updated: 14/04/2021
Causes and Pathophysiology
FCS is a monogenic disease with different pattern of inheritance. In 80-90% of patients with FCS, low activity of lipoprotein lipase (LPL) is caused by mutations in the gene that encodes this enzyme.
Symptoms and complications
Learn more about the broad spectrum of signs and symptoms that are associated with FCS.
Diagnosis
FCS diagnosis is based on a three-step approach:
- High triglyceride evaluation
- Identification of candidates for FCS genetic testing
- Genetic test of possible affected genes