Spotlight FCS for Health Care Professionals

Triglycerides
- What are they?

The role and importance of triglycerides in the body

What are triglycerides?

Triglycerides make up the majority of dietary fats and serve as a vital energy source for your body. When you consume more calories than your body needs, these extra calories are converted into triglycerides and stored in fat tissue.1

How triglycerides work

During meals, fats are transported from your intestines into your blood in the form of triglycerides. These triglycerides are then absorbed by muscles, fat tissue, and organs for energy use. Triglycerides can also be formed from sugar (such as those found in soft drinks and juices) and alcohol.1

Transporting triglycerides

Triglycerides cannot travel through the blood on their own. They are carried by particles called chylomicrons, which act as transport vehicles.1

Breaking down triglycerides

An enzyme called lipoprotein lipase (LPL) breaks down triglycerides transported in chylomicrons, releasing free fatty acids that your body can use for energy.2

Why fats are important

Fats, including triglycerides, are an essential energy source. They help store energy from the food you eat and release it when your body needs it.

What happens when triglyceride levels are too high?

If triglyceride levels in your blood become too high, this is called hypertriglyceridemia. This condition can lead to various symptoms and complications including acute pancreatitis, making it important to manage your triglyceride levels for overall health.3

Triglyceride

Causes of high triglyceride levels

High triglyceride levels, also known as hypertriglyceridemia, indicate a disorder of fat metabolism.

Learn more about HTG

Learn more about FCS, familial chylomicronemia syndrome

Familial chylomicronemia syndrome, FCS is a form of severe hypertriglyceridemia that is genetically inherited

Learn more about FCS

References

  1. Bashir, B. et al. Severe Hypertriglyceridaemia and Chylomicronaemia Syndrome—Causes, Clinical Presentation, and Therapeutic Options. Metabolites 2023, 13, 621.
  2. Brunzell JD, Bierman EL. Chylomicronemia Syndrome, Interaction of Genetic and Acquired Hpertriglyceridemia. Med Clin North Am 1982;66(2):455–68;
  3. Davidson M, et al. The burden of familial chylomicronemia syndrome: Results from the global IN-FOCUS study. J Clin Lipidol 2018;12(4):898–907.

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